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KMID : 0366919970090010059
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Sungkyun Pharmceutical Journal
1997 Volume.9 No. 1 p.59 ~ p.60
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A Formal Total Synthesis of(±)-Ferruginine by Pd-catalyzed Intramolecular Aminocarbonylation
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Ham, Won-Hun
Jung, Young Hoon/Lee, Kyunghae/Oh, Chang-Young/Lee, Kee-Young
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Abstract
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A practical and efficient synthetic route to the neuroactive alkaloid ferruginine has been developed. 8-Azabicyclo[3. 2. 1]octane skeleton 4 was prepared in one step by intramolecular aminocarbonylation of 3 catalyzed by palladium.
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